Ioxaglic acid impurity A CRS

Ioxaglic acid impurity A CRS - Names and Identifiers

Name	5-AMINO-N-(2-HYDROXYETHYL)-2,4,6-TRIIODOISOPHTHALAMIC ACID
Synonyms	Ioxilan Related CoMpound A Ioxaglic acid impurity A CRS 5-AMINO-N-(2-HYDROXYETHYL)-2,4,6-TRIIODOISOPHTHALAMIC ACID 5-amino- N-(2- hydroxyethyl)-2,4,6-triiodo-methylbenzoic acid 2,4,6-Triiodo-3-(N-hydroxyethylcarbamoyl)-5-aminobenzoic Acid 3-AMINO-5-[(2-HYDROXYETHYL)CARBAMOYL]-2,4,6-TRIIODOBENZOIC ACID 3-Amino-5-[(2-hydroxyethyl)carbamoyl]-2,4,6-triiodobenzoic acid benzoic acid, 3-amino-5-[[(2-hydroxyethyl)amino]carbonyl]-2,4,6-triiodo- IOXILAN RELATED COMPOUND A (100 MG) (5-AMINO-2,4,6-TRIIODO-3 N-(2-HYDROXYETHYL)CARBA-MOYL BENZOIC ACID) IOXILAN RELATED COMPOUND A (100 MG) (5-AMINO-2,4,6-TRIIODO-3 N-(2-HYDROXYETHYL)CARBA-MOYL BENZOIC ACID)
CAS	22871-58-5
InChI	InChI=1/C10H9I3N2O4/c11-5-3(9(17)15-1-2-16)6(12)8(14)7(13)4(5)10(18)19/h16H,1-2,14H2,(H,15,17)(H,18,19)

Ioxaglic acid impurity A CRS - Physico-chemical Properties

Molecular Formula	C10H9I3N2O4
Molar Mass	601.9
Density	2.677±0.06 g/cm3(Predicted)
Boling Point	520.5±50.0 °C(Predicted)
Flash Point	268.6°C
Vapor Presure	1.16E-11mmHg at 25°C
Appearance	neat
Color	White
pKa	1.22±0.10(Predicted)
Storage Condition	Refrigerator
Refractive Index	1.798

Ioxaglic acid impurity A CRS - Risk and Safety

HS Code

2924296000

Ioxaglic acid impurity A CRS - Introduction

5-AMINO-N-(2-HYDROXYETHYL)-2,4,6-TRIIODOISOPHTHALAMIC ACID is an organic compound commonly abbreviated as AMIPA. The Following are details of the properties, use, preparation and safety information of the compound:

Nature:
-Appearance: White crystalline solid
-Solubility: Soluble in water and alcohol solvents
-Melting point: About 200 ° C
-Molecular formula: C10H8I3NO4
-Molecular weight: 614.89g/mol

Use:
- 5-AMINO-N-(2-HYDROXYETHYL)-2,4,6-TRIIODOISOPHTHALAMIC ACID is used as a carrier of radionuclides for thyroid scanning and is also used for thyroid function evaluation and treatment of hyperthyroidism.
-It can also be used as a surgical marker in thyroid surgery to help locate and protect thyroid tissue.

Method:
The preparation method of-5-AMINO-N-(2-HYDROXYETHYL)-2,4,6-TRIIODOISOPHTHALAMIC ACID is complicated and requires special chemical synthesis technology. In general, P-Hydroxybenzoic acid is used for multi-step reactions, including ethylation, triiodination, etc.

Safety Information:
- 5-AMINO-N-(2-HYDROXYETHYL)-2,4,6-TRIIODOISOPHTHALAMIC ACID has low toxicity when used correctly.
-When handling and using the compound, follow relevant safety procedures, including wearing personal protective equipment such as protective gloves and masks, and storing it in a sealed container, avoid contact with skin and eyes.
-When disposing of waste, it should be disposed of correctly in accordance with local regulations to avoid pollution to the environment.

Please note that the compound is radioactive and should only be used by professionals under suitable equipment and conditions. During use, please follow all relevant safety instructions.

Last Update：2024-04-10 22:29:15